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by Kogushi, M. et al.Eisai Tsukuba Research Laboratories, Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba, JapanThe novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial...

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by Altarescu, G. et al.Genetics Unit, Shaare Zedek Medical Center, IsraelThe [-1426(C/T)] polymorphic variant of PAR1 is associated with thrombocytopenia in Gaucher disease.Blood Cells Mol. Dis. 2010;...

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by Bae, J.S. et al.Edward A Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St Louis, Missouri 63104, USAFactor X/Xa elicits protective signaling...

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by Silini, A. et al.Laboratory of Biology and Treatment of Metastases, Department of Oncology, Mario Negri Institute for Pharmacological Research, Milan, ItalyThe migration and invasion capabilities...

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by McCoy, K.L. et al.Department of Pharmacology, Rollins Research Center, Emory University School of Medicine, Atlanta, USAPAR1 effects on ERK1/2 phosphorylation and cell migration were blocked both...

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by Smadja, D.M. et al.Université Paris Descartes, Faculté de Pharmacie, Paris, FranceTarget-specific siRNA-induced PAR-1 knockdown, and fully inhibited PAR-1-induced IL-8 synthesis.J. Cell. Mol. Med....

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by Banfi, C. et al.Monzino Cardiologic Center IRCCS, Milan, ItalyMitochondrial reactive oxygen species: a common pathway for PAR1- and PAR2-mediated tissue factor induction in human endothelial...

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by Hernández, N.A. et al.Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Mexico City, MexicoTwenty-nine of 50 (58%) patients overexpressed PAR1, and 23 of these (46%)...

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by Grisaru-Granovsky, S. et al.Department of Oncology, Hadassah-University Medical Center, Jerusalem, IsraelProtease activated receptor-1, PAR1, promotes placenta trophoblast invasion and beta-catenin...

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by Chintala, M. et al.Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USAPreclinical and clinical studies have confirmed that SCH 530348, a potent, orally active...

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by Gudmundsdóttir, I.J. et al.Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United KingdomRole of the endothelium in the vascular effects of the thrombin receptor...

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by Gigante, B. et al.Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Division of Pharmacology, Federico II University, ItalyRetrospective analysis of coagulation factor II...

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by Loberg, R.D. et al.Department of Urology, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USAFurther exploration is needed to determine whether PAR1 activation...

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